When a person uses heroine there will be both short-term and long-term effects. In the short-term, individuals may feel a rush, their mouth may become dry, their hands, arms and legs may fee heavy and they their skin may feel warm.  After the rush subsides, a person may begin to nod off.  This is when they will go in and out of being in and out of full consciousness. It may be difficult for them to think clearly, their speech may be slurred and they will likely be difficult to understand. They may walk slow, have trouble sleeping at night, become constipated and/or vomit.

If a person begins to abuse heroine there will be long term affects.  That person risks developing abscesses and infections of the heart valve and lining.  Their veins may collapse and they may also developing liver disease.  A tolerance can also develop which can put the user at risk for an overdose. Because they will need to take an increasing amount of the drug in order to feel its effects, they often take large doses which can result in death.